7 research outputs found

    Architecture de communication pour les réseaux d’instrumentation sans fil

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    Aujourd'hui les réseaux de capteurs sont devenus des systèmes pouvant atteindre un très grand nombre de noeuds, avec une zone de couverture déterminée et déployés d'une manière plus ou moins dense dans un environnement hétérogène dont on mesure ainsi son état global. La problématique de cette thèse consiste à concevoir une architecture pour les objets communicants à faible consommation en utilisant des antennes « intelligentes » pour l'instrumentation et la mesure. Intégrant une approche pluridisciplinaire, cette architecture couvre les services offerts depuis les couches MAC jusqu'à celles de plus haut niveau. Basés sur une partie matérielle complètement reconfigurable (amplificateur de puissance et antennes à base de MEMS RF), les services des couches supérieures sont définis en partie sur circuits numériques pour la couche physique (bande de base) et la couche MAC, et de manière logicielle pour les protocoles de routages adaptés et les services innovants. En résumé, le travail consiste à concevoir un système autonome multi capteurs, d'acquisition et de traitement avec mémorisation, communicant à travers un réseau sans fil. Les principaux problèmes à résoudre seront : le contrôle de la topologie, la précision de la synchronisation, la consommation d'énergie. ABSTRACT : Researches in the field of sensor networks show the variety and vastness of applications in which these types of systems are used. One of their main features is the large number (up to hundreds of elements) of sensors that must be distributed in different environments. Another concern consists in making routing decisions in order to reduce the energy consumption. Depending on the application requirements, ensuring synchronous network functionality is currently a challenge. The issue addressed in this thesis is to develop an architecture for smart objects using low-power antennas for structural heald monitoring. Integrating a multidisciplinary approach, this architecture includes services from the MAC layer to those of the highest level. In summary, we will develop an autonomous system ofi sensors, for acquisition and information processing, which communicate via a wireless network. The main problems are: the control of topology, the timing accuracy and the energy consumption

    Serological Parameters and Vascular Investigation for a Better Assessment in DVT during Pregnancy—A Systematic Review

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    Pregnancy and the postpartum period represent a condition characterized by a thrombotic predisposition. The majority of pregnant women do not face acute or severe thrombotic events. In general, mild inconveniences such as leg swelling or moderately painful thrombotic events (phlebitis) are encountered. However, when pregnancy is associated with inherited or acquired deficits that affect homeostasis, the risk of acute or even life-threatening events can increase significantly. The major consequence is the loss of the fetus or the venous thromboembolism that endangers the mother’s life. Venous thromboembolism is caused by deep vein thrombosis, therefore timely detection and especially the assessment of the extent of the thrombotic event are crucial. In this paper we have summarized the most important paraclinical investigations. The study emphasizes the importance of selecting the methods of investigation. The right choice allows establishing a correct diagnosis and individualizing the treatment

    Obtaining, Evaluation, and Optimization of Doxycycline-Loaded Microparticles Intended for the Local Treatment of Infectious Arthritis

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    Compared to the classical systemic administration, the local drug release has some advantages, such as lack of systemic toxicity and associated side effects, increased patient compliance, and a low rate of bacterial resistance. Biopolymers are widely used to design sustained drug delivery systems and biomaterials for tissue engineering. Type II collagen is the indispensable component in articular cartilage and plays a critical role in the growth and proliferation process of chondrocytes. Thus, type II collagen has drawn more attention and interest in the treatment and research of the cartilage regeneration. The aim of this study was to obtain, characterize, and optimize the microcapsules formulation based on type II collagen, sodium alginate, and sodium carboxymethyl cellulose loaded with doxycycline as an antibiotic model drug that could be incorporated further in hydrogels to improve the localized therapy of septic arthritis. The new synthesized microcapsules were assessed by spectral (FT-IR), morphological (optical microscopy), and biological analysis (enzymatic biodegradation, antimicrobial activity). The size distribution of the obtained microcapsules was determined using optical microscopy. The drug encapsulation efficiency was also determined. To optimize the microcapsules’ composition, some physical-chemical and biological analyses were subjected to an optimization technique based on experimental design, response surface methodology, and the Taguchi technique, and the adequate formulations were selected. The results obtained recommend these new microcapsules as promising drug systems to be further incorporated in type II collagen hydrogels used for septic arthritis

    Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications

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    We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications

    The 12th Edition of the Scientific Days of the National Institute for Infectious Diseases “Prof. Dr. Matei Bals” and the 12th National Infectious Diseases Conference

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